The Profound Autism Summit is a two-day conference bringing together leaders from the areas of research, medicine, treatment, advocacy, and education to discuss the needs and support of those with Profound Autism across disciplines and throughout the lifespan.

Profound Autism refers to autistic individuals who have significant intellectual and communication challenges, requiring 24/7 support. The Lancet Commission first proposed the term "Profound Autism" in their December 2021 report. This new classification highlights the distinct needs of this population, giving families, advocates, and providers a way to describe the unique needs of this group.